p144: review of deep brain stimulation target areas in patients with obsessive-compulsive disorder
نویسندگان
چکیده
obsessive-compulsive disorder (ocd) is a psychiatric disorder manifested by thoughts and impulses that produce anxiety and result in patients performing repetitive rituals. treatment generally consists of cognitive behavioral intervention and serotonin reuptake inhibitors. up to 40% of patients will have functional impairment that significantly affects their quality of life. in the late 1990’s, based on positive research results in anterior capsulotomies, deep brain stimulation (dbs) researchers first implanted electrodes in the anterior capsule of treatment-resistant ocd patients. the early results were promising. three of the first four patients experienced benefit. a worldwide study found that out of 26 patients with treatment-resistant ocd, 61.5% responded positively to dbs. this response rate is similar to the other surgeries described above. however, comparisons must be tentative since the number of patients treated with dbs is still relatively small. in this review we discuss about the target area of dbs in ocd. since then, larger trials have been done and the target area of the brain has moved slightly to an overlapping part of the brain called the ventral capsule/ventral striatum.
منابع مشابه
P144: Review of Deep Brain Stimulation Target Areas in Patients with Obsessive-Compulsive Disorder
Obsessive-compulsive disorder (OCD) is a psychiatric disorder manifested by thoughts and impulses that produce anxiety and result in patients performing repetitive rituals. Treatment generally consists of cognitive behavioral intervention and serotonin reuptake inhibitors. Up to 40% of patients will have functional impairment that significantly affects their quality of life. In the late 1990’s,...
متن کاملDeep brain stimulation in obsessive-compulsive disorder.
The use of deep brain stimulation in psychiatric disorders has received great interest owing to the small risk of the operation, the reversible nature of the technique, and the possibility of optimizing treatment postoperatively. Currently, deep brain stimulation in psychiatry is investigated for obsessive-compulsive disorder, Gilles de la Tourette's syndrome, and major depression. This chapter...
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BACKGROUND Deep brain stimulation (DBS) is a promising treatment for treatment-refractory obsessive-compulsive disorder (OCD). However, the effects of DBS on cognitive functioning remain unclear. Therefore, we aimed to assess cognitive safety of DBS for treatment-refractory OCD and the association between clinical changes and cognitive functioning. METHODS Patients with treatment-refractory O...
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BACKGROUND Obsessive-compulsive disorder (OCD) is a chronic neuropsychiatric disorder with a 2% to 3% lifetime prevalence; in addition, 10% of OCD patients are resistant to conventional therapy. Deep brain stimulation (DBS) has been an effective treatment for treatment resistant OCD patients (TROCD). We aimed to determine the cost-effectiveness of DBS for TROCD. METHODS We used a Markov model...
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BACKGROUND Obsessive-compulsive disorder is one of the most disabling of all psychiatric illnesses. Despite available pharmacological and psychotherapeutic treatments about 10% of patients remain severely affected and are considered treatment-refractory. For some of these patients deep brain stimulation offers an appropriate treatment method. The scope of this article is to review the published...
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عنوان ژورنال:
مجله علوم اعصاب شفای خاتمجلد ۲، شماره ۳، صفحات ۱۶۸-۱۶۸
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